Phenotypes Associated with This Genotype

Genotype
MGI:3717126

cx13

• Allelic Composition: Myo1e^{Gt(ROSA)74Sor}/Myo1e^{Gt(ROSA)74Sor}; Pdgfrb^tm1Sor/Pdgfrb⁺
• Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvEvBrd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

hematopoietic system phenotype ( J:117491 )

N • anemia seen in Myo1e^{Gt(ROSA)74Sor} is rescued

renal/urinary system

abnormal renal glomerulus morphology ( J:117491 )

• glomeruli are often swollen and degraded

• smooth muscle cell number is reduced in the glomeruli

abnormal kidney physiology ( J:117491 )

• decrease in kidney function

muscle

abnormal smooth muscle morphology ( J:117491 )

• smooth muscle cell number is reduced in the glomeruli

homeostasis/metabolism

increased blood urea nitrogen level ( J:117491 )