Phenotypes for Krt8 Tnfrsf1b MGI:3711995 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Krt8^tm1Rgo/Krt8^tm1Rgo Tnfrsf1b^tm1Mwm/Tnfrsf1b^tm1Mwm
Genetic Background	involves: 129S2/SvPas * C57BL/6 * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Krt8^tm1Rgo mutation (1 available); any Krt8 mutation (30 available)
Tnfrsf1b^tm1Mwm mutation (2 available); any Tnfrsf1b mutation (37 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality during organogenesis, incomplete penetrance ( J:121811 )

• survival improved 4 fold in the absence of maternal TNFRSF1b as compared to the condition in which TNFRSF1b was present

• survival continues to be reduced

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/24/2026 MGI 6.24