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Phenotypes Associated with This Genotype
Genotype
MGI:3693680
Allelic
Composition
Fbxo11Jf/Fbxo11Mutt
Genetic
Background
involves: BALB/c * C3H/HeN
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbxo11Jf mutation (2 available); any Fbxo11 mutation (51 available)
Fbxo11Mutt mutation (0 available); any Fbxo11 mutation (51 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• a small proportion (12%) of compound heterozygous showed perinatal lethality similar to Fbxo11Jf/Fbxo11Jf or similar to Fbxo11Mutt/Fbxo11Mutt

hearing/vestibular/ear
• reduced hearing in response to a click box similar to Fbxo11Jf heterozygotes
• similar to Fbxo11Jf/Fbxo11+

immune system
• similar to Fbxo11Jf/Fbxo11+

craniofacial
• shortened face similar to Fbxo11Jf/Fbxo11+
• in some similar to Fbxo11Jf/Fbxo11Jf or similar to Fbxo11Mutt/Fbxo11Mutt

growth/size/body
• shortened face similar to Fbxo11Jf/Fbxo11+
• in some similar to Fbxo11Jf/Fbxo11Jf or similar to Fbxo11Mutt/Fbxo11Mutt

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
otitis media DOID:10754 J:114851


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory