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Phenotypes Associated with This Genotype
Genotype
MGI:3693665
Allelic
Composition		 Fbxo11Jf/Fbxo11+
Genetic
Background		 involves: BALB/cAnNCrl * C3H/HeN * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbxo11Jf mutation (2 available); any Fbxo11 mutation (54 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
increased susceptibility to otitis media ( J:114851 )
• otitis media was clearly evident by 28 days of age onwards
• no cleft palate was observed at any stage

immune system
increased susceptibility to otitis media ( J:114851 )
• otitis media was clearly evident by 28 days of age onwards
• no cleft palate was observed at any stage

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
otitis media DOID:10754 J:114851

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/07/2025
MGI 6.24 		The Jackson Laboratory