Phenotypes Associated with This Genotype

Genotype
MGI:3620078

hm1

• Allelic Composition: Col1a1^Mov13/Col1a1^Mov13
• Genetic Background: C57BL/6-Col1a1^Mov13

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

decreased bone ossification ( J:16630 )

• bone development and extent of ossification is markedly reduced when prospective bone-forming regions (parts of the lower jaw or central portion of the limbs of E12.5-13.5 embryos) are transplanted under the kidney capsule of adult wild-type hosts or onto chorioallantoic membrane of 8 day chick embryos

delayed bone ossification ( J:16630 )

• bone formation is initiated in two embryos that survive to E16, however bone development is retarded and does not progress to later stages of endochondrial ossification