Phenotypes Associated with This Genotype

Genotype
MGI:3619449

• Allelic Composition: Sufu^tm1Rto/Sufu⁺
• Genetic Background: involves: 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

pigmentation

abnormal coat/hair pigmentation ( J:105832 )

• increased pigmentation

integument

abnormal coat/hair pigmentation ( J:105832 )

• increased pigmentation

alopecia ( J:105832 )

• ventral alopecia

abnormal epidermis stratum basale morphology ( J:105832 )

• papules start out at 6 months of age as small evaginations from the basal epidermis on the palmar aspect of paws

• expand with time

abnormal skin appearance ( J:105832 )

• papules and nodules are visible on the paws and tail starting around 1.5 years of age

• become progressively worse with age

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
nevoid basal cell carcinoma syndrome		DOID:2512	OMIM:PS109400	J:105832