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Phenotypes Associated with This Genotype
Genotype
MGI:3609905
Allelic
Composition		 Slco1a5tm1Lex/Slco1a5tm1Lex
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slco1a5tm1Lex mutation (2 available); any Slco1a5 mutation (54 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased B cell number ( J:103485 )
• increase in mean percentage of B cells in the peripheral blood
abnormal CD8-positive, alpha beta T cell morphology ( J:103485 )
• decrease in mean percentage of CD8 cells

hematopoietic system
increased B cell number ( J:103485 )
• increase in mean percentage of B cells in the peripheral blood
abnormal CD8-positive, alpha beta T cell morphology ( J:103485 )
• decrease in mean percentage of CD8 cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/24/2026
MGI 6.24 		The Jackson Laboratory