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Phenotypes Associated with This Genotype
Genotype
MGI:3590140
Allelic
Composition
GckRgsc735/Gck+
Genetic
Background
involves: C57BL/6J * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
GckRgsc735 mutation (1 available); any Gck mutation (59 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• increased glycosylated hemoglobin indicating a prolonged increase in serum glucose
• mutants have a free fed serum glucose level of 200 mg/dl or more, this was the basis for selection in the ENU screen

hematopoietic system
• increased glycosylated hemoglobin indicating a prolonged increase in serum glucose

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
maturity-onset diabetes of the young type 2 DOID:0111100 OMIM:125851
J:88919


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory