Phenotypes Associated with This Genotype

Genotype
MGI:3588732

• Allelic Composition: Cln8^mnd/Cln8^mnd
• Genetic Background: AK.B6(Cg)-Cln8^mnd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:56219 )

• Background Sensitivity: die by 5.5 months of age

nervous system

abnormal motor neuron morphology ( J:56219 )

• Background Sensitivity: motor neuron disease is accelerated even more than in the mixed AKR/J and B6.KB2 background, with symptoms appearing by 4 months and death by 5.5 months of age

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
neuronal ceroid lipofuscinosis 8		DOID:0110723	OMIM:600143	J:56219