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Phenotypes Associated with This Genotype
Genotype
MGI:3587787
Allelic
Composition		 Pitx2tm1Jfm/Pitx2tm2Jfm
Genetic
Background		 involves: 129S4/SvJaeSor
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pitx2tm1Jfm mutation (1 available); any Pitx2 mutation (42 available)
Pitx2tm2Jfm mutation (0 available); any Pitx2 mutation (42 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial
arrest of tooth development ( J:87220 )
• molars arrest prior to cap formation

growth/size/body
arrest of tooth development ( J:87220 )
• molars arrest prior to cap formation

skeleton
arrest of tooth development ( J:87220 )
• molars arrest prior to cap formation

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
Axenfeld-Rieger syndrome type 1 DOID:0110120 OMIM:180500
 J:87220

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory