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Phenotypes Associated with This Genotype
Genotype
MGI:3582549
Allelic
Composition
Twist1Ska10/Twist1+
Genetic
Background
C57BL/6J-Twist1Ska10
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Twist1Ska10 mutation (1 available); any Twist1 mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail
• heterozygotes have extra digits on both hindlimbs

skeleton
• heterozygotes exhibit craniosynostosis with irregular lamboidal and coronal suture lines; at P10, mutant skulls have abnormally closed sutures


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory