Phenotypes Associated with This Genotype

Genotype
MGI:3579845

• Allelic Composition: Tbx20^tm1.1Rph/Tbx20⁺
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

dilated heart left atrium ( J:98489 )

• left atrial dilation is seen

decreased heart left ventricle wall thickness ( J:98489 )

• left ventricular wall thickness was decreased by 35%

dilated heart left ventricle ( J:98489 )

• the left ventricle diastolic dimension is mildly but significantly increased

dilated cardiomyopathy ( J:98489 )

• signs of dilated cardiomyopathy are seen but no compensatory myocardial hypertrophy or change in heart weight are detected

decreased ventricle muscle contractility ( J:98489 )

• left ventricular systolic dimension was increased 42% and fractional shortening was decreased by 21%

muscle

dilated cardiomyopathy ( J:98489 )

• signs of dilated cardiomyopathy are seen but no compensatory myocardial hypertrophy or change in heart weight are detected

decreased ventricle muscle contractility ( J:98489 )

• left ventricular systolic dimension was increased 42% and fractional shortening was decreased by 21%

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
dilated cardiomyopathy		DOID:12930	OMIM:PS115200	J:98489