Phenotypes for Nyx MGI:3055970 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Nyx^nob/Nyx^nob
Genetic Background	BALB/c-Nyx^nob

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Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nyx^nob mutation (0 available); any Nyx mutation (3 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

abnormal eye electrophysiology ( J:50824 )

• does not display electroretinographic (ERG) b-waves

• ERG finding is observed by day 18

abnormal cone electrophysiology ( J:50824 )

• light-adapted cone ERG retains a negative polarity

abnormal rod electrophysiology ( J:50824 )

• dark-adapted rod ERG retains a negative polarity even with increasing stimulus intensity

absent visual evoked potential ( J:50824 )

• no response to visual evoked potential at flash onset and slight response at flash offset

abnormal vision ( J:81028 )

• decreased light sensitivity

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
congenital stationary night blindness 1A		DOID:0110870	OMIM:310500	J:50824

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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