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Phenotypes Associated with This Genotype
Genotype
MGI:3051563
Allelic
Composition		 Clnktm1Vei/Clnktm1Vei
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Clnktm1Vei mutation (0 available); any Clnk mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:91590 )
N
• except as noted, these mice were perfectly normal
abnormal mast cell physiology ( J:91590 )
• slightly enhanced IL-3 induced proliferation
increased natural killer cell mediated cytotoxicity ( J:91590 )
• enhanced cytotoxicity observed against several cell lines

hematopoietic system
abnormal mast cell physiology ( J:91590 )
• slightly enhanced IL-3 induced proliferation
increased natural killer cell mediated cytotoxicity ( J:91590 )
• enhanced cytotoxicity observed against several cell lines

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory