Phenotypes Associated with This Genotype

Genotype
MGI:3036179

• Allelic Composition: Ccnd1^tm1Wbg/Ccnd1^tm1Wbg; Ccnd3^tm1Pisc/Ccnd3^tm1Pisc
• Genetic Background: involves: 129S2/SvPas

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, incomplete penetrance ( J:80994 )

• while mice were born near the expected frequency, most died within the first day demonstrating impaired suckling

• some mice survived the perinatal period

behavior/neurological

abnormal suckling behavior ( J:80994 )

growth/size/body

decreased body size ( J:80994 )

• mice that survived the perinatal period did not thrive and were much smaller than wild-type littermates in spite of a calorie-rich diet

respiratory system

aspiration ( J:80994 )

• suggestions of acute asphyxiation caused by meconium aspiration syndrome

vision/eye

retina hypoplasia ( J:80994 )