About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3032571
Allelic
Composition
Tgcog/Tgcog
Genetic
Background
involves: AKR/J * C57BL/6By
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tgcog mutation (2 available); any Tg mutation (146 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
• hypertrophy of thyrofollicular cells

growth/size/body
• evident at day 15 postnatal (J:3079)
• evident by 15 days postnatal (J:8567)
• repaired when diet at weaning was supplemented with desiccated thyroid powder (J:8567)

hematopoietic system

homeostasis/metabolism

nervous system
• cerebrum and cerebellum weighed significantly less than littermate controls
• brain stem weight equivalent to littermate controls
• hypomyelination, restricted to cerebrum

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
congenital hypothyroidism DOID:0050328 OMIM:PS275200
J:8567


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
07/02/2024
MGI 6.13
The Jackson Laboratory