Phenotypes Associated with This Genotype

Genotype
MGI:2683906

• Allelic Composition: Blm^tm3Brd/Blm^tm3Brd
• Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased tumor incidence ( J:66261 )

• tumor development after 1 year of age

• 29% of mice with tumors by 20 months

increased lymphoma incidence ( J:66261 )

• about 60% of spontaneous tumors are lymphomas

immune system

decreased IgM level ( J:66261 )

• concentration reduced by 10%

hematopoietic system

decreased IgM level ( J:66261 )

• concentration reduced by 10%

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Bloom syndrome		DOID:2717	OMIM:210900	J:66261