Phenotypes for Pafah1b1 MGI:2664549 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Pafah1b1^tm1Or/Pafah1b1⁺
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pafah1b1^tm1Or mutation (0 available); any Pafah1b1 mutation (158 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal radial glial cell morphology ( J:69631 )

• abnormal organization of radial glia

abnormal telencephalon development ( J:69631 )

• abnormal emergence of cortical plate in caudal and medial regions of dorsal telencephalon

delayed brain development ( J:69631 )

• delayed formation of the cortical plate

• delayed neuronal migration in the cortex

cellular

abnormal radial glial cell morphology ( J:69631 )

• abnormal organization of radial glia

Mouse Models of Human Disease	DO ID	OMIM ID(s)	Ref(s)
lissencephaly	DOID:0050453	OMIM:PS607432	J:69631
Miller-Dieker lissencephaly syndrome	DOID:0060469	OMIM:247200	J:69631

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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