Phenotypes Associated with This Genotype

Genotype
MGI:2446508

• Allelic Composition: Abcc8^tm1.1Mgn/Abcc8^tm1.1Mgn
• Genetic Background: involves: 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

decreased insulin secretion ( J:79352 )

• impaired glucose-stimulated insulin secretion, but normal secretion with normal diet

homeostasis/metabolism

decreased insulin secretion ( J:79352 )

• impaired glucose-stimulated insulin secretion, but normal secretion with normal diet

hypoglycemia ( J:79352 )

• developed with age, beginning at 12 - 16 weeks

impaired glucose tolerance ( J:79352 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
NOT	hyperinsulinemic hypoglycemia	DOID:13317	OMIM:PS256450	J:79352