Phenotypes for Twist1 MGI:2177042 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Twist1^Pde/Twist1^Pde
Genetic Background	involves: 129S1/Sv * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Twist1^Pde mutation (1 available); any Twist1 mutation (20 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• animals resorbed by E11

nervous system

open neural tube ( J:69450 )

• failure of neural tube closure

exencephaly ( J:69450 )

embryo

open neural tube ( J:69450 )

• failure of neural tube closure

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Saethre-Chotzen syndrome		DOID:14768	OMIM:101400 OMIM:180750	J:69450

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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