Phenotypes Associated with This Genotype

Genotype
MGI:2175741

• Allelic Composition: Pax6^132-14Neu/Pax6⁺
• Genetic Background: involves: 101 * C3H

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

fused cornea and lens ( J:6686 )

• the remnants of the pupillary membrane connect the opacity with the cornea

abnormal lens vesicle development ( J:6686 )

• failure of lens vesicle to separate from ectoderm

cataract ( J:6686 )

• pyramidal opacity at anterior pole of lens; uni- or bilateral and incomplete penetrance

• the opacity frequently protrudes into the anterior chamber and attaches to the cornea

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
cataract		DOID:83	OMIM:601371 OMIM:PS116200	J:6686