All Phenotypes Gja1<tm1.1Dalil> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Gja1^tm1.1Dalil
targeted mutation 1.1, Dali Luo
MGI:8448960

Summary

2 genotypes

Allelic Composition	Gja1^tm1.1Dalil/Gja1^tm1.1Dalil
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gja1^tm1.1Dalil mutation (0 available); any Gja1 mutation (62 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

Allelic Composition	Gja1^tm1.1Dalil/Gja1⁺
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gja1^tm1.1Dalil mutation (0 available); any Gja1 mutation (62 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

increased heart weight ( J:292392 )

• increased heart to body weight ratio in mice presenting with ventricular tachycardia at age 10 days

irregular heartbeat ( J:292392 )

• spontaneous arrhythmia in 66% of mice at age 10 days

ventricular tachycardia ( J:292392 )

• at age 10 days

ventricular premature beat ( J:292392 )

• at age 10 days

cellular

increased cardiomyocyte apoptosis ( J:292392 )

growth/size/body

increased heart weight ( J:292392 )

• increased heart to body weight ratio in mice presenting with ventricular tachycardia at age 10 days

mortality/aging

• 30% die between age 9 and 21 days

muscle

increased cardiomyocyte apoptosis ( J:292392 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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