Phenotypes associated with this allele

• Allele Symbol: Twist1^m1Yiji
• Allele Name: mutation 1, Yichang Jia
• Allele ID: MGI:8409643
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Twist1^m1Yiji/Twist1^m1Yiji	C57BL/6J-Twist1^m1Yiji	MGI:8409879
ht2	Twist1^m1Yiji/Twist1^+	C57BL/6J-Twist1^m1Yiji	MGI:8409878

Genotype
MGI:8409879

hm1

• Allelic Composition: Twist1^m1Yiji/Twist1^m1Yiji
• Genetic Background: C57BL/6J-Twist1^m1Yiji

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

lethality throughout fetal growth and development, complete penetrance ( J:285540 )

• no mice born

Genotype
MGI:8409878

ht2

• Allelic Composition: Twist1^m1Yiji/Twist1⁺
• Genetic Background: C57BL/6J-Twist1^m1Yiji

behavior/neurological

decreased social novelty preference ( J:285540 )

limbs/digits/tail

polydactyly ( J:285540 )

• in hindlimbs

skeleton

skeleton phenotype ( J:285540 )

N • no pre-fusion of coronal and lambdoid sutures

premature sagittal suture closure ( J:285540 )

vision/eye

ocular hypertelorism ( J:285540 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Saethre-Chotzen syndrome		DOID:14768	OMIM:101400 OMIM:180750	J:285540