About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Gt(ROSA)26Sorem3.1(CAG-MTRFR)Rwb
endonuclease-mediated mutation 3.1, Robert W Burgess
MGI:8407860
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Gt(ROSA)26Sorem3.1(CAG-MTRFR)Rwb/Gt(ROSA)26Sor+
Mtrfrem9Rwb/Mtrfrem9Rwb
involves: C57BL/6J MGI:8407861


Genotype
MGI:8407861
cx1
Allelic
Composition
Gt(ROSA)26Sorem3.1(CAG-MTRFR)Rwb/Gt(ROSA)26Sor+
Mtrfrem9Rwb/Mtrfrem9Rwb
Genetic
Background
involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sorem3.1(CAG-MTRFR)Rwb mutation (0 available); any Gt(ROSA)26Sor mutation (1209 available)
Mtrfrem9Rwb mutation (0 available); any Mtrfr mutation (13 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
N
• The expression of human wild type MTRFR allowed homozygous Mtrfr mutant mice to survive when normally they die before E12.5.





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
07/14/2026
MGI 6.24
The Jackson Laboratory