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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tex51em1Osb
endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
MGI:8395587
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Tex51em1Osb/Tex51em1Osb B6;D2-Tex51em1Osb/Osb MGI:8395589


Genotype
MGI:8395589
hm1
Allelic
Composition
Tex51em1Osb/Tex51em1Osb
Genetic
Background
B6;D2-Tex51em1Osb/Osb
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tex51em1Osb mutation (0 available); any Tex51 mutation (5 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
N
• both sexes exhibit normal fecundity; despite abnormal head morphogenesis, adult males sire pups with normal average litter sizes when paired with wild-type females and show no significant changes in testis weight-to-body weight ratio, testis and epididymis histology, or sperm motility parameters including progressive motility
• over 80% of spermatozoa exhibit head malformations

cellular
• over 80% of spermatozoa exhibit head malformations





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/08/2026
MGI 6.24
The Jackson Laboratory