All Phenotypes Trpv4<em2Lutzy> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Trpv4^em2Lutzy
endonuclease-mediated mutation 2, Cathy Lutz
MGI:8332032

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Trpv4^em2Lutzy/Trpv4⁺	involves: C57BL/6J	MGI:8332067

Allelic Composition	Trpv4^em2Lutzy/Trpv4⁺
Genetic Background	involves: C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Trpv4^em2Lutzy mutation (0 available); any Trpv4 mutation (59 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

impaired balance ( J:352175 )

• increased latency to fall in horizontal balance test

hunched posture ( J:352175 )

• difficulty maintaining upright head posture

akinesia ( J:352175 )

• no ambulation in hours before death

forelimb paralysis ( J:352175 )

craniofacial

domed cranium ( J:352175 )

short snout ( J:352175 )

embryo

embryo phenotype ( J:352175 )

N	• mice born at expected Mendelian ratios

growth/size/body

short snout ( J:352175 )

mortality/aging

respiratory system

respiratory distress ( J:352175 )

• labored breathing in hours before death

skeleton

domed cranium ( J:352175 )

kyphosis ( J:352175 )

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