About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cacna1dem1Cont
endonuclease-mediated mutation 1, Anis Contractor
MGI:8323031
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Cacna1dem1Cont/Cacna1dem1Cont
Tg(Drd1-tdTomato)5Calak/0 		involves: C57BL/6 * C57BL/6J * SJL MGI:8323041


Genotype
MGI:8323041
cx1
Allelic
Composition		 Cacna1dem1Cont/Cacna1dem1Cont
Tg(Drd1-tdTomato)5Calak/0
Genetic
Background		 involves: C57BL/6 * C57BL/6J * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cacna1dem1Cont mutation (0 available); any Cacna1d mutation (118 available)
Tg(Drd1-tdTomato)5Calak mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
reduced long-term depression ( J:353799 )
• impaired nitric oxide (NO)-dependent long-term postsynaptic depression (NO-LTD) of glutamatergic striatal spiny projection neuron (SPN) synapses




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/07/2026
MGI 6.24 		The Jackson Laboratory