Phenotypes associated with this allele

• Allele Symbol: Tn(pb-Act-RFP)1.100309034-HRAZhu
• Allele Name: transposon insertion 1.100309034-HRA, Yuan Zhuang
• Allele ID: MGI:8292667
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tn(pb-Act-RFP)1.100309034-HRAZhu/Tn(pb-Act-RFP)1.100309034-HRAZhu	involves: FVB/NJ	MGI:8297271
ot2	Tn(pb-Act-RFP)1.100309034-HRAZhu/0	involves: FVB/NJ	MGI:8297272

Genotype
MGI:8297271

hm1

• Allelic Composition: Tn(pb-Act-RFP)1.100309034-HRAZhu/Tn(pb-Act-RFP)1.100309034-HRAZhu
• Genetic Background: involves: FVB/NJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:378174 )

• lethal at P10 and subviable at E18.5

perinatal lethality, incomplete penetrance ( J:378174 )

• mice are subviable at E18.5

growth/size/body

embryonic growth retardation ( J:378174 )

• early developmental delay

embryo

embryonic growth retardation ( J:378174 )

• early developmental delay

cardiovascular system

abnormal cardiovascular development ( J:378174 )

• embryos exhibit cardiovascular defects

abnormal vascular development ( J:378174 )

• vascular system abnormalities

liver/biliary system

abnormal liver development ( J:378174 )

• liver abnormalities

Genotype
MGI:8297272

ot2

• Allelic Composition: Tn(pb-Act-RFP)1.100309034-HRAZhu/0
• Genetic Background: involves: FVB/NJ

adipose tissue

decreased total body fat amount ( J:378174 )

♂ • male mice fail to build up regular levels of adipose tissue and exhibit less fat

♂ • male mice show decreased fat/lean ratio, decreased fat mass/body weight ratio, increased lean mass/body weight ratio, decreased fat mass, and no difference in lean mass weight

decreased percent body fat/body weight ( J:378174 )

♂ • males exhibit reduced fat mass/body weight ratio

growth/size/body

increased body weight ( J:378174 )

♂ • males exhibit increased body weight