Phenotypes associated with this allele

• Allele Symbol: Morrbid^{Tn(pb-Act-RFP)1.091029285-HRAZhu}
• Allele Name: transposon insertion 1.091029285-HRA, Yuan Zhuang
• Allele ID: MGI:8292631
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Morrbid^Tn(pb-Act-RFP)1.091029285-HRAZhu/Morrbid^Tn(pb-Act-RFP)1.091029285-HRAZhu	involves: C57BL/6	MGI:8296706
ht2	Morrbid^Tn(pb-Act-RFP)1.091029285-HRAZhu/Morrbid^+	involves: C57BL/6	MGI:8296707

Genotype
MGI:8296706

hm1

• Allelic Composition: Morrbid^{Tn(pb-Act-RFP)1.091029285-HRAZhu}/Morrbid^{Tn(pb-Act-RFP)1.091029285-HRAZhu}
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

embryonic growth retardation ( J:378174 )

• developmental delay

mortality/aging

postnatal lethality, complete penetrance ( J:378174 )

• mice are viable at E10.5, E12.5, E15.5, and E18.5, and lethal at P10

growth/size/body

embryonic growth retardation ( J:378174 )

• developmental delay

cardiovascular system

abnormal cardiovascular development ( J:378174 )

• embryos exhibit cardiovascular defects

abnormal vascular development ( J:378174 )

• vascular system abnormalities

liver/biliary system

abnormal liver development ( J:378174 )

• liver abnormalities

Genotype
MGI:8296707

ht2

• Allelic Composition: Morrbid^{Tn(pb-Act-RFP)1.091029285-HRAZhu}/Morrbid⁺
• Genetic Background: involves: C57BL/6

adipose tissue

increased total body fat amount ( J:378174 )

♂ • males show reduced lean mass/body weight ratio