mortality/aging
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• mice are viable at E10.5, subviable at E12.5, E15.5, and E18.5, and lethal at P10
|
|
• embryos are subviable at E12.5
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growth/size/body
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• early developmental delay
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embryo
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• early developmental delay
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cardiovascular system
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• embryos exhibit cardiac phenotypes
|
|
• vascular system abnormalities
|
liver/biliary system
|
• liver abnormalities
|
nervous system
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• brain malformation
|


Analysis Tools