mortality/aging
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• mice are viable at E10.5 and E12.5, subviable at E15.5 and lethal at E18.5
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• mice are viable at E12.5 but subviable at E15.5
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growth/size/body
cardiovascular system
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• embryos exhibit cardiac phenotypes
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• vascular system abnormalities
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liver/biliary system
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• liver abnormalities
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Analysis Tools