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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Etv6Tn(pb-Act-RFP)1.1081125037-HLAZhu
transposon insertion 1. 081125037-HLA, Yuan Zhuang
MGI:8292573
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Etv6Tn(pb-Act-RFP)1.1081125037-HLAZhu/Etv6Tn(pb-Act-RFP)1.1081125037-HLAZhu involves: FVB/NJ MGI:8296210


Genotype
MGI:8296210
hm1
Allelic
Composition		 Etv6Tn(pb-Act-RFP)1.1081125037-HLAZhu/Etv6Tn(pb-Act-RFP)1.1081125037-HLAZhu
Genetic
Background		 involves: FVB/NJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Etv6Tn(pb-Act-RFP)1.1081125037-HLAZhu mutation (0 available); any Etv6 mutation (144 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality prior to heart atrial septation, complete penetrance ( J:378174 )
• mice are subviable at E12.5 and lethal at E15.5

growth/size/body
abnormal body size ( J:378174 )

cardiovascular system
abnormal cardiovascular development ( J:378174 )
• embryos exhibit cardiac phenotypes
abnormal vascular development ( J:378174 )
• vascular system abnormalities

liver/biliary system
abnormal liver development ( J:378174 )
• liver abnormalities

nervous system
abnormal brain development ( J:378174 )
• embryos exhibit brain defects




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory