Phenotypes associated with this allele

• Allele Symbol: Gpr107^{Tn(pb-Act-RFP)1.090514011-HRAZhu}
• Allele Name: transposon insertion 1.090514011-HRA, Yuan Zhuang
• Allele ID: MGI:8292571
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gpr107^Tn(pb-Act-RFP)1.090514011-HRAZhu/Gpr107^Tn(pb-Act-RFP)1.090514011-HRAZhu	involves: FVB/NJ	MGI:8296207
ht2	Gpr107^Tn(pb-Act-RFP)1.090514011-HRAZhu/Gpr107^+	involves: FVB/NJ	MGI:8296208

Genotype
MGI:8296207

hm1

• Allelic Composition: Gpr107^{Tn(pb-Act-RFP)1.090514011-HRAZhu}/Gpr107^{Tn(pb-Act-RFP)1.090514011-HRAZhu}
• Genetic Background: involves: FVB/NJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:378174 )

• mice are viable at E10.5 but exhibit lethality at E12.5

cardiovascular system

abnormal cardiovascular development ( J:378174 )

• embryos exhibit cardiac phenotypes

abnormal vascular development ( J:378174 )

• vascular system abnormalities

liver/biliary system

abnormal liver development ( J:378174 )

• liver abnormalities

Genotype
MGI:8296208

ht2

• Allelic Composition: Gpr107^{Tn(pb-Act-RFP)1.090514011-HRAZhu}/Gpr107⁺
• Genetic Background: involves: FVB/NJ

growth/size/body

increased lean body mass ( J:378174 )

♂ • male mice show increased lean mass/body weight ratio, no difference in fat mass, and increase in lean mass weight

increased body weight ( J:378174 )

♂ • males at 4 weeks of age are heavier than wild-type mice