Phenotypes associated with this allele

• Allele Symbol: Gm3867^{Tn(pb-Act-RFP)1.100318002-HLAZhu}
• Allele Name: transposon insertion 1.100318002-HLA, Yuan Zhuang
• Allele ID: MGI:8292545
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gm3867^Tn(pb-Act-RFP)1.100318002-HLAZhu/Gm3867^Tn(pb-Act-RFP)1.100318002-HLAZhu	involves: FVB/NJ	MGI:8293326
ht2	Gm3867^Tn(pb-Act-RFP)1.100318002-HLAZhu/Gm3867^+	involves: FVB/NJ	MGI:8293327

Genotype
MGI:8293326

hm1

• Allelic Composition: Gm3867^{Tn(pb-Act-RFP)1.100318002-HLAZhu}/Gm3867^{Tn(pb-Act-RFP)1.100318002-HLAZhu}
• Genetic Background: involves: FVB/NJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality, complete penetrance ( J:378174 )

• lethal before E10.5

growth/size/body

embryonic growth retardation ( J:378174 )

• early developmental delay

embryo

embryonic growth retardation ( J:378174 )

• early developmental delay

cardiovascular system

abnormal cardiovascular development ( J:378174 )

• embryos exhibit cardiac phenotypes

abnormal vascular development ( J:378174 )

• vascular system abnormalities

liver/biliary system

abnormal liver development ( J:378174 )

• liver abnormalities

Genotype
MGI:8293327

ht2

• Allelic Composition: Gm3867^{Tn(pb-Act-RFP)1.100318002-HLAZhu}/Gm3867⁺
• Genetic Background: involves: FVB/NJ

nervous system

abnormal nervous system development ( J:378174 )

• embryos exhibit central nervous system development delays at E10.5