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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dlatem2Cya
endonuclease-mediated mutation 2, Cyagen Biosciences
MGI:8280685
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Dlatem2Cya/Dlatem2Cya involves: C57BL/6J MGI:8290522
ht2
 		Dlatem2Cya/Dlat+ involves: C57BL/6J MGI:8290521


Genotype
MGI:8290522
hm1
Allelic
Composition		 Dlatem2Cya/Dlatem2Cya
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dlatem2Cya mutation (0 available); any Dlat mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:8290521
ht2
Allelic
Composition		 Dlatem2Cya/Dlat+
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dlatem2Cya mutation (0 available); any Dlat mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased incidence of tumors by chemical induction ( J:367681 )
• in a diethyl nitrosamine/carbon tetrachloride-induced hepatocellular carcinoma model mice show reduced reduced tumor burden in both number and volume

neoplasm
decreased incidence of tumors by chemical induction ( J:367681 )
• in a diethyl nitrosamine/carbon tetrachloride-induced hepatocellular carcinoma model mice show reduced reduced tumor burden in both number and volume




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory