Phenotypes associated with this allele

• Allele Symbol: Ccdc152^em1Ktmr
• Allele Name: endonuclease-mediated mutation 1, Kentaro Tanemura
• Allele ID: MGI:8273657
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ccdc152^em1Ktmr/Ccdc152^em1Ktmr	C57BL/6N-Ccdc152^em1Ktmr	MGI:8275616

Genotype
MGI:8275616

hm1

• Allelic Composition: Ccdc152^em1Ktmr/Ccdc152^em1Ktmr
• Genetic Background: C57BL/6N-Ccdc152^em1Ktmr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

reproductive system phenotype ( J:377007 )

♂N • males produce normal size litters when mated with wild-type females

♂N • no abnormalities in spermatogenesis are detected

teratozoospermia ( J:377007 )

♂ • both head and flagellar abnormalities are detected in cauda spermatozoa

♂ • however, sperm motility is normal

small seminiferous tubules ( J:377007 )

♂ • decreased circumference

decreased testis weight ( J:377007 )

♂ • testis/body weight ratio is reduced

♂ • epididymal/body weight ratio is similar to controls

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:377007 )

N • no alteration in selenoprotein expression in the liver, blood, or testes

cellular

teratozoospermia ( J:377007 )

♂ • both head and flagellar abnormalities are detected in cauda spermatozoa

♂ • however, sperm motility is normal

endocrine/exocrine glands

small seminiferous tubules ( J:377007 )

♂ • decreased circumference

decreased testis weight ( J:377007 )

♂ • testis/body weight ratio is reduced

♂ • epididymal/body weight ratio is similar to controls