About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Bmpr2tm1.2Nwm
targeted mutation 1.2, Nicholas W Morrell
MGI:8255475
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Bmpr2tm1.2Nwm/Bmpr2+ Not Specified MGI:8255484


Genotype
MGI:8255484
ht1
Allelic
Composition		 Bmpr2tm1.2Nwm/Bmpr2+
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bmpr2tm1.2Nwm mutation (0 available); any Bmpr2 mutation (46 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
cardiovascular system phenotype ( J:367200 )
N
• no changes in right ventricular systolic pressure and no right ventricular hypertrophy (RVH)
• no changes in pulmonary artery wall thickness, with or without 4PBA treatment

respiratory system
abnormal pulmonary alveolar duct morphology ( J:367200 )
• reduced alveolar duct artery muscularization after 4PBA treatment: increase in nonmuscularized and decrease in partially muscularized vessels




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory