Phenotypes associated with this allele

• Allele Symbol: Ufsp1^em1Ics
• Allele Name: endonuclease-mediated mutation 1, Mouse Clinical Institute
• Allele ID: MGI:8255237
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ufsp1^em1Ics/Ufsp1^em1Ics	involves: C57BL/6NCrl	MGI:8255239

Genotype
MGI:8255239

hm1

• Allelic Composition: Ufsp1^em1Ics/Ufsp1^em1Ics
• Genetic Background: involves: C57BL/6NCrl

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal neuromuscular synapse morphology ( J:372394 )

• motor neuron axons and nerve terminals are decreased in the neuromuscular junction (NMJ) and the degree of NMJ innervation in fast-twitch type muscle is reduced (defined by overlap of AChR and motor neuron axons), indicating a small decrease of the presynaptic area

muscle

muscle phenotype ( J:372394 )

N • mice show no gross abnormalities up to 1 year, with normal weights of tibialis anterior and soleus muscles, and normal cross-sectional areas of myofibers in both fast-twitch and slow-twitch muscles indicating no major structural abnormalities in skeletal muscle