All Phenotypes Tubb4b<em6Golab> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tubb4b^em6Golab
endonuclease-mediated mutation 6, Genetic in Ophtalmology Laboratory
MGI:8249379

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Tubb4b^em6Golab/Tubb4b⁺	C57BL/6J-Tubb4b^em6Golab	MGI:8328274

Allelic Composition	Tubb4b^em6Golab/Tubb4b⁺
Genetic Background	C57BL/6J-Tubb4b^em6Golab

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tubb4b^em6Golab mutation (0 available); any Tubb4b mutation (15 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

cellular

• loss of tracheal cilia

nervous system

hydrocephaly ( J:360308 )

reproductive system

abnormal spermatogenesis ( J:360308 )

respiratory system

• loss of tracheal cilia

abnormal mucociliary clearance ( J:360308 )

• mice exhibit mucopurulent nasal plugs

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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