Phenotypes associated with this allele

• Allele Symbol: Cgnl1^tm1.1Citi
• Allele Name: targeted mutation 1.1, Sandra Citi
• Allele ID: MGI:8244802
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cgnl1^tm1.1Citi/Cgnl1^tm1.1Citi	involves: 129 * C57BL/6	MGI:8244993

Genotype
MGI:8244993

hm1

• Allelic Composition: Cgnl1^tm1.1Citi/Cgnl1^tm1.1Citi
• Genetic Background: involves: 129 * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

digestive/alimentary system

abnormal intestinal epithelium morphology ( J:345322 )

• apical localization of CAMSAP3 is lost

• nuclei in the villi and crypts are not aligned with some ectopically shifted into the apical region

• while the average cell height is similar to controls, they show a wider range of cell heights

• microtubules are more randomly oriented with a mean crossing angle of 40.35^o compared to 27.44^o in controls