Phenotypes associated with this allele

• Allele Symbol: Trp53bp1^{em1(IMPC)Ccpcz}
• Allele Name: endonuclease-mediated mutation 1, Institute of Molecular Genetics
• Allele ID: MGI:8234011
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Trp53bp1^em1(IMPC)Ccpcz/Trp53bp1^em1(IMPC)Ccpcz	C57BL/6NCrl-Trp53bp1^em1(IMPC)Ccpcz/Ccpcz	MGI:8298552

Genotype
MGI:8298552

hm1

• Allelic Composition: Trp53bp1^{em1(IMPC)Ccpcz}/Trp53bp1^{em1(IMPC)Ccpcz}
• Genetic Background: C57BL/6NCrl-Trp53bp1^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Trp53bp1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal heart left ventricle morphology ( J:211773 )

♂

IMPC - CCP-IMG

decreased cardiac output ( J:211773 )

♂

IMPC - CCP-IMG

decreased cardiac stroke volume ( J:211773 )

♂

IMPC - CCP-IMG

increased cardiac muscle contractility ( J:211773 )

♂

IMPC - CCP-IMG

hematopoietic system

abnormal spleen morphology ( J:211773 )

IMPC - CCP-IMG

small spleen ( J:211773 )

♂

IMPC - CCP-IMG

immune system

abnormal spleen morphology ( J:211773 )

IMPC - CCP-IMG

small spleen ( J:211773 )

♂

IMPC - CCP-IMG

integument

abnormal skin morphology ( J:211773 )

IMPC - CCP-IMG

muscle

increased cardiac muscle contractility ( J:211773 )

♂

IMPC - CCP-IMG

respiratory system

abnormal lung morphology ( J:211773 )

IMPC - CCP-IMG

skeleton

abnormal bone structure ( J:211773 )

♂

IMPC - CCP-IMG