About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Sel1l2em1Osb
endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
MGI:8224224
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Sel1l2em1Osb/Sel1l2em1Osb B6;D2-Sel1l2em1Osb/Osb MGI:8288888


Genotype
MGI:8288888
hm1
Allelic
Composition		 Sel1l2em1Osb/Sel1l2em1Osb
Genetic
Background		 B6;D2-Sel1l2em1Osb/Osb
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sel1l2em1Osb mutation (1 available); any Sel1l2 mutation (41 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:370030 )
N
• males exhibit normal testis gross appearance, testis weight/body weight ratios, testis and epididymis histology, and cauda epididymal sperm morphology and motility with no major changes in sperm kinetic parameters relative to aged-matched heterozygous littermates; males sire pups with normal average litter sizes when paired with wild-type females




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory