Analysis Tools|
Allele Symbol Allele Name Allele ID |
Gpr45em2Zz endonuclease-mediated mutation 2, Zhao Zhang MGI:8215535 |
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| Summary |
4 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• mice injected with an adeno-associated virus (AAV) expressing cre recombinase into the paraventricular nucleus of the hypothalamus exhibit increased body weight, fat weight and lean weight by 7 weeks after injection
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• mice exhibit normal body weight and fat weight even at 16 weeks of age
• mice fed a high-fat diet starting at 6 weeks of age and maintained for 4 weeks do not develop obesity
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• mice exhibit increased body weight, fat weight and lean weight at 16 weeks of age
|
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• mice fed a high-fat diet starting at 6 weeks of age and maintained for 4 weeks exhibit increased body weight and fat weight
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• mice fed a high-fat diet starting at 6 weeks of age and maintained for 4 weeks exhibit increased body weight and fat weight
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• mice exhibit increased body weight, fate weight and lean weight at 16 weeks of age
|
|
• mice fed a high-fat diet starting at 6 weeks of age and maintained for 4 weeks exhibit increased body weight and fat weight
|
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• mice fed a high-fat diet starting at 6 weeks of age and maintained for 4 weeks exhibit increased body weight and fat weight
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/30/2025 MGI 6.24 |
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