Analysis Tools|
Allele Symbol Allele Name Allele ID |
Gpr45em2Zz endonuclease-mediated mutation 2, Zhao Zhang MGI:8215535 |
||||||||||||||||||||
| Summary |
4 genotypes
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• mice injected with an adeno-associated virus (AAV) expressing cre recombinase into the paraventricular nucleus of the hypothalamus exhibit increased body weight, fat weight and lean weight by 7 weeks after injection
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• mice exhibit normal body weight and fat weight even at 16 weeks of age
• mice fed a high-fat diet starting at 6 weeks of age and maintained for 4 weeks do not develop obesity
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• mice exhibit increased body weight, fat weight and lean weight at 16 weeks of age
|
|
• mice fed a high-fat diet starting at 6 weeks of age and maintained for 4 weeks exhibit increased body weight and fat weight
|
|
• mice fed a high-fat diet starting at 6 weeks of age and maintained for 4 weeks exhibit increased body weight and fat weight
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• mice exhibit increased body weight, fate weight and lean weight at 16 weeks of age
|
|
• mice fed a high-fat diet starting at 6 weeks of age and maintained for 4 weeks exhibit increased body weight and fat weight
|
|
• mice fed a high-fat diet starting at 6 weeks of age and maintained for 4 weeks exhibit increased body weight and fat weight
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 03/25/2025 MGI 6.24 |
|
|
|
||
