Phenotypes associated with this allele

• Allele Symbol: Wwtr1^{em1(IMPC)Ccpcz}
• Allele Name: endonuclease-mediated mutation 1, Institute of Molecular Genetics
• Allele ID: MGI:8213648
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Wwtr1^em1(IMPC)Ccpcz/Wwtr1^em1(IMPC)Ccpcz	C57BL/6NCrl-Wwtr1^em1(IMPC)Ccpcz/Ccpcz	MGI:8298571
ht2	Wwtr1^em1(IMPC)Ccpcz/Wwtr1^+	C57BL/6NCrl-Wwtr1^em1(IMPC)Ccpcz/Ccpcz	MGI:8298570

Genotype
MGI:8298571

hm1

• Allelic Composition: Wwtr1^{em1(IMPC)Ccpcz}/Wwtr1^{em1(IMPC)Ccpcz}
• Genetic Background: C57BL/6NCrl-Wwtr1^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Wwtr1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

abnormal testis morphology ( J:211773 )

♂

IMPC - CCP-IMG

small testis ( J:211773 )

♂

IMPC - CCP-IMG

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - CCP-IMG

renal/urinary system

abnormal kidney morphology ( J:211773 )

♂

IMPC - CCP-IMG

reproductive system

abnormal testis morphology ( J:211773 )

♂

IMPC - CCP-IMG

small testis ( J:211773 )

♂

IMPC - CCP-IMG

respiratory system

abnormal lung morphology ( J:211773 )

♂

IMPC - CCP-IMG

Genotype
MGI:8298570

ht2

• Allelic Composition: Wwtr1^{em1(IMPC)Ccpcz}/Wwtr1⁺
• Genetic Background: C57BL/6NCrl-Wwtr1^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Wwtr1

cardiovascular system

abnormal retina vasculature morphology ( J:211773 )

IMPC - CCP-IMG

abnormal heart morphology ( J:211773 )

♂

IMPC - CCP-IMG

enlarged heart ( J:211773 )

♂

IMPC - CCP-IMG

increased cardiac output ( J:211773 )

♂

IMPC - CCP-IMG

craniofacial

abnormal tooth color ( J:211773 )

♂

IMPC - CCP-IMG

growth/size/body

enlarged heart ( J:211773 )

♂

IMPC - CCP-IMG

abnormal tooth color ( J:211773 )

♂

IMPC - CCP-IMG

enlarged lung ( J:211773 )

♂

IMPC - CCP-IMG

enlarged spleen ( J:211773 )

IMPC - CCP-IMG

hematopoietic system

increased mean corpuscular hemoglobin concentration ( J:211773 )

♀

IMPC - CCP-IMG

decreased mean corpuscular volume ( J:211773 )

♀

IMPC - CCP-IMG

abnormal spleen morphology ( J:211773 )

IMPC - CCP-IMG

enlarged spleen ( J:211773 )

IMPC - CCP-IMG

immune system

abnormal spleen morphology ( J:211773 )

IMPC - CCP-IMG

enlarged spleen ( J:211773 )

IMPC - CCP-IMG

integument

abnormal coat/hair pigmentation ( J:211773 )

♂

IMPC - CCP-IMG

abnormal skin morphology ( J:211773 )

IMPC - CCP-IMG

pigmentation

abnormal coat/hair pigmentation ( J:211773 )

♂

IMPC - CCP-IMG

renal/urinary system

abnormal kidney morphology ( J:211773 )

♀

IMPC - CCP-IMG

small kidney ( J:211773 )

♀

IMPC - CCP-IMG

respiratory system

abnormal lung morphology ( J:211773 )

♂

IMPC - CCP-IMG

enlarged lung ( J:211773 )

♂

IMPC - CCP-IMG

skeleton

abnormal tooth color ( J:211773 )

♂

IMPC - CCP-IMG

vision/eye

abnormal eye morphology ( J:211773 )

♀

IMPC - CCP-IMG

abnormal retina vasculature morphology ( J:211773 )

IMPC - CCP-IMG