Phenotypes associated with this allele

• Allele Symbol: Tmem81^em1Osb
• Allele Name: endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
• Allele ID: MGI:8193005
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tmem81^em1Osb/Tmem81^em1Osb	involves: C57BL/6J * DBA/2J	MGI:8275269

Genotype
MGI:8275269

hm1

• Allelic Composition: Tmem81^em1Osb/Tmem81^em1Osb
• Genetic Background: involves: C57BL/6J * DBA/2J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

male infertility ( J:363713 )

♂ • males are infertile, however testes appear normal and sperm have normal morphology and motility

impaired fertilization ( J:363713 )

• sperm do not fertilize cumulus-intact, cumulus-free, and zona pellucida-free eggs in vitro

failure of sperm-egg fusion ( J:363713 )

• sperm can bind the oolemma but are unable to fuse with it