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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		+
wild type
MGI:7855114
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Del(3Bglap2-Bglap)2Kry/+
Ptprvtm1Kry/Ptprvtm1Kry
Tg(Col1a1-cre)1Kry/0 		involves: 129S7/SvEvBrd * FVB MGI:3763094
cn2
 		Del(3Bglap2-Bglap)2Kry/+
Ggcxtm1.1Kry/Ggcxtm1.1Kry
Tg(BGLAP-cre)1Clem/0 		involves: 129S7/SvEvBrd * FVB/NJ MGI:6198739
cx3
 		Adipoqtm1Ish/Adipoq+
Del(3Bglap2-Bglap)2Kry/+ 		involves: 129S7/SvEvBrd MGI:3763093


Genotype
MGI:3763094
cn1
Allelic
Composition		 Del(3Bglap2-Bglap)2Kry/+
Ptprvtm1Kry/Ptprvtm1Kry
Tg(Col1a1-cre)1Kry/0
Genetic
Background		 involves: 129S7/SvEvBrd * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(3Bglap2-Bglap)2Kry mutation (0 available); any Del(3Bglap2-Bglap)2Kry mutation (0 available)
Ptprvtm1Kry mutation (0 available); any Ptprv mutation (30 available)
Tg(Col1a1-cre)1Kry mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
homeostasis/metabolism phenotype ( J:126780 )
N
• unlike in Ptprvtm1Kry/ Ptprvtm1Kry Tg(Col1a1-cre)1Kry mice, glucose homeostasis is normal

endocrine/exocrine glands
endocrine/exocrine gland phenotype ( J:126780 )
N
• unlike in Ptprvtm1Kry/ Ptprvtm1Kry Tg(Col1a1-cre)1Kry mice, beta-cell proliferation is normal




Genotype
MGI:6198739
cn2
Allelic
Composition		 Del(3Bglap2-Bglap)2Kry/+
Ggcxtm1.1Kry/Ggcxtm1.1Kry
Tg(BGLAP-cre)1Clem/0
Genetic
Background		 involves: 129S7/SvEvBrd * FVB/NJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(3Bglap2-Bglap)2Kry mutation (0 available); any Del(3Bglap2-Bglap)2Kry mutation (0 available)
Ggcxtm1.1Kry mutation (0 available); any Ggcx mutation (35 available)
Tg(BGLAP-cre)1Clem mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
homeostasis/metabolism phenotype ( J:264734 )
N
• glucose tolerance is normal




Genotype
MGI:3763093
cx3
Allelic
Composition		 Adipoqtm1Ish/Adipoq+
Del(3Bglap2-Bglap)2Kry/+
Genetic
Background		 involves: 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adipoqtm1Ish mutation (0 available); any Adipoq mutation (42 available)
Del(3Bglap2-Bglap)2Kry mutation (0 available); any Del(3Bglap2-Bglap)2Kry mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
insulin resistance ( J:126780 )
• mice exhibit decreased insulin sensitivity
• however, blood glucose levels, insulin serum levels, and insulin secretion are normal




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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory