Phenotypes associated with this allele

• Allele Symbol: Ints15^em1(IMPC)Bay
• Allele Name: endonuclease-mediated mutation 1, Baylor College of Medicine
• Allele ID: MGI:7780097
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ints15^em1(IMPC)Bay/Ints15^em1(IMPC)Bay	C57BL/6N-Ints15^em1(IMPC)Bay/Bay	MGI:8298340
ht2	Ints15^em1(IMPC)Bay/Ints15^+	C57BL/6N-Ints15^em1(IMPC)Bay/Bay	MGI:8298339

Genotype
MGI:8298340

hm1

• Allelic Composition: Ints15^em1(IMPC)Bay/Ints15^em1(IMPC)Bay
• Genetic Background: C57BL/6N-Ints15^em1(IMPC)Bay/Bay

Data Sources

IMPC Data for Ints15

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal heart morphology ( J:211773 )

IMPC - BCM

embryo

abnormal embryo turning ( J:211773 )

IMPC - BCM

embryonic growth retardation ( J:211773 )

IMPC - BCM

abnormal tail bud morphology ( J:211773 )

IMPC - BCM

abnormal allantois morphology ( J:211773 )

IMPC - BCM

growth/size/body

embryonic growth retardation ( J:211773 )

IMPC - BCM

homeostasis/metabolism

edema ( J:211773 )

♂

IMPC - BCM

limbs/digits/tail

abnormal tail bud morphology ( J:211773 )

IMPC - BCM

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - BCM

preweaning lethality, complete penetrance ( J:211773 )

IMPC - BCM

nervous system

abnormal forebrain development ( J:211773 )

♂

IMPC - BCM

Genotype
MGI:8298339

ht2

• Allelic Composition: Ints15^em1(IMPC)Bay/Ints15⁺
• Genetic Background: C57BL/6N-Ints15^em1(IMPC)Bay/Bay

Data Sources

IMPC Data for Ints15

behavior/neurological

decreased grip strength ( J:211773 )

♀

IMPC - BCM