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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		rnv5
retinal neovascularization 5
MGI:7707431
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Crb1rd8/Crb1rd8
rnv5/rnv5+ 		B6N.Cg-rnv5/BocJ MGI:7707433
cx2
 		Crb1rd8/Crb1+
rnv5/rnv5+ 		Not Specified MGI:7707445


Genotype
MGI:7707433
cx1
Allelic
Composition		 Crb1rd8/Crb1rd8
rnv5/rnv5+
Genetic
Background		 B6N.Cg-rnv5/BocJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crb1rd8 mutation (18 available); any Crb1 mutation (92 available)
rnv5 mutation (1 available); any rnv5 mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Significant retinal neovascularization in Crb1rd8/Crb1rd8 \AlleleSymbolMGI(7707431|0)/rnv5+ mice by 4 weeks of age

vision/eye
retina neovascularization ( J:352529 )
• neovascularization by 3 weeks of age

cardiovascular system
retina neovascularization ( J:352529 )
• neovascularization by 3 weeks of age




Genotype
MGI:7707445
cx2
Allelic
Composition		 Crb1rd8/Crb1+
rnv5/rnv5+
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crb1rd8 mutation (18 available); any Crb1 mutation (92 available)
rnv5 mutation (1 available); any rnv5 mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
vision/eye phenotype ( J:352529 )
N
• No abnormal ocular phenotype in rnv5 carriers that are heterozygous for the rd8 allele




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory