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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pycr1em1Zhob
endonuclease-mediated mutation 1, Binquan Zhou
MGI:7624490
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pycr1em1Zhob/Pycr1em1Zhob involves: C57BL/6N MGI:7624493


Genotype
MGI:7624493
hm1
Allelic
Composition		 Pycr1em1Zhob/Pycr1em1Zhob
Genetic
Background		 involves: C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pycr1em1Zhob mutation (0 available); any Pycr1 mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
decreased susceptibility to myocardial ischemic injury ( J:345302 )
• reduced myocardial fibrosis and improved cardiac function after ligation of the left anterior descending coronary artery compared to similarly treated wild-type controls
decreased myocardial infarct size ( J:345302 )
• decreased infarct size after ligation of the left anterior descending coronary artery

homeostasis/metabolism
decreased susceptibility to myocardial ischemic injury ( J:345302 )
• reduced myocardial fibrosis and improved cardiac function after ligation of the left anterior descending coronary artery compared to similarly treated wild-type controls
decreased myocardial infarct size ( J:345302 )
• decreased infarct size after ligation of the left anterior descending coronary artery




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory