All Phenotypes Eogt<tm1.1Okaj> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Eogt^tm1.1Okaj
targeted mutation 1.1, Tetsuya Okajima
MGI:7607995

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Eogt^tm1.1Okaj/Eogt^tm1.1Okaj Tg(Tek-cre)1Ywa/0	involves: C57BL/6 * C57BL/6J * SJL	MGI:7640065

Allelic Composition	Eogt^tm1.1Okaj/Eogt^tm1.1Okaj Tg(Tek-cre)1Ywa/0
Genetic Background	involves: C57BL/6 * C57BL/6J * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eogt^tm1.1Okaj mutation (0 available); any Eogt mutation (44 available)
Tg(Tek-cre)1Ywa mutation (7 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

abnormal retina vasculature morphology ( J:254752 )

• vessel branching is increased in P5 and P15 retinas

• however, length of alphaSMA+ vessels and vessel progression in P5 retinas is not altered

increased vascular permeability ( J:254752 )

• retinas show aberrant fibrinogen staining and sulfo-NHS-LC-biotin extravasation indicating reduced vessel integrity

vision/eye

abnormal retina vasculature morphology ( J:254752 )

• vessel branching is increased in P5 and P15 retinas

• however, length of alphaSMA+ vessels and vessel progression in P5 retinas is not altered

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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